“Backs founders turning new crypto infrastructure into products people use every day: stablecoins and cross-border payments, onchain finance and capital markets, tokenized real-world assets, creator platforms, and AI agents and autonomous networks.”
Portfolio splits below are computed from the 24 companies named on the a16z crypto portfolio page that we could classify, not from the full 100+ list.
a16z crypto is the crypto arm of Andreessen Horowitz, run as a set of dedicated funds under founder and managing partner Chris Dixon. Across five funds the group has raised more than $9.8 billion, and the fifth fund, announced on May 5, 2026, is $2.2 billion. The Fund 5 letter is unusually explicit about what it wants: stablecoins and cross-border payments, onchain finance and capital markets (perpetual futures, prediction markets, lending), tokenization of real-world assets, decentralized creator platforms, and AI agents and autonomous networks. The framing is "durable adoption rather than speculation", which tells you how to pitch.
The firm operates like a platform rather than a cheque-writer. It runs a research group, an engineering team that publishes open-source work, a go-to-market team, and a policy team in Washington, and it publishes heavily: the annual Big Ideas list, State of Crypto reports, and long-form essays. Founders who read that output before pitching arrive with a shared vocabulary.
For early teams the entry point is the Crypto Startup Accelerator (CSX). It has run in London, New York and San Francisco, invests a minimum of $500,000 per company (the Fall 2024 terms were $500,000 for 7% equity plus standard rights), lasts eight to ten weeks in person, and ends with a Demo Day. Alumni on the CSX page include Phantom, Goldfinch, Flashbots, Notional, Pimlico and Neynar.
Key stats:
| Partner | Role | Where to find them |
|---|---|---|
| Chris Dixon | Founder and Managing Partner | @cdixon on X, a16zcrypto.com/team/chris-dixon |
| Ali Yahya | General Partner | a16zcrypto.com/team |
| Guy Wuollet | General Partner (also on the CSX team) | a16zcrypto.com/accelerator/people |
| Eddy Lazzarin | General Partner (CTO) | a16zcrypto.com/team |
| Arianna Simpson | General Partner | a16zcrypto.com/team/arianna-simpson |
| Carra Wu, Elizabeth Harkavy, Sam Broner | Investment Partners, CSX | CSX people page |
| Maggie Hsu | Head of Go-to-market | CSX people page |
X and LinkedIn handles beyond Chris Dixon's were not verified on the team pages we fetched, so we have linked the team pages instead of guessing handles.